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Kawasaki disease: Part II. Complications and treatment
Kawasaki disease, or mucocutaneous lymph node syndrome, is the leading cause of acquired heart disease in children in the United States and other developed countries. Coronary artery lesions are the most significant cause of morbidity and mortality. Treatment should ideally be provided within 10 days of symptom onset to reduce the risk of coronary artery complications. The standard of care for treatment is intravenous immunoglobulin plus aspirin, but adding corticosteroids may provide additional benefit for high-risk patients. Some patients do not respond to intravenous immunoglobulin and require additional therapy. Part I...
Source: Journal of the American Academy of Dermatology - September 20, 2013 Category: Dermatology Authors: Stephanie Bayers, Stanford T. Shulman, Amy S. Paller Tags: Continuing Medical Education Source Type: research

U.S. Medical Schools Are Struggling to Overcome Centuries of Racism in Health Care
Derrick Morton was skeptical about working for Kaiser Permanente’s Bernard J. Tyson School of Medicine. The Pasadena, Calif., school hadn’t yet opened to students when he was offered a job in early 2020, and it felt risky to work for such a new institution. But Morton, who is Black, was eventually sold by the medical school’s mission: to train doctors with a strong focus on diversity, equity, and inclusion and to dismantle health disparities. After a short time as an assistant professor of biomedical science, however, Morton says it became clear that the reality didn’t live up to his “great ex...
Source: TIME: Health - August 29, 2022 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Equality feature healthscienceclimate Source Type: news

Primary care providers ’ awareness, knowledge, and practice with regard to cardiovascular risk in patients with rheumatoid arthritis
This study is a cross-sectional survey with the purpose of evaluating primary care providers ’ awareness, practice patterns, and satisfaction with continuing medical education on cardiovascular risk in patients with RA. Our study showed that 71% of clinicians felt that the CME on RA patient management regarding CV risk factors is inadequate. Only 37% of providers reported feeling well pre pared to manage CV risk for RA patients. Only 15% of participants were actively initiating a discussion regarding CV risk with RA patients. A better understanding of the educational needs and practice patterns of primary care providers ...
Source: Clinical Rheumatology - December 23, 2019 Category: Rheumatology Source Type: research

Polycythemia vera and essential thrombocythemia: 2013 update on diagnosis, risk‐stratification, and management
Disease OverviewPolycythemia Vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms (MPN) primarily characterized by erythrocytosis and thrombocytosis, respectively. Other disease features include leukocytosis, splenomegaly, thrombohemorrhagic complications, vasomotor disturbances, pruritus and a small risk of disease progression into acute myeloid leukemia or myelofibrosis. DiagnosisAlmost all patients with PV harbor a JAK2 mutation. When PV is suspected, the presence of a JAK2 mutation highly suggests the diagnosis and its absence, combined with normal or increased serum erythropoietin level, exclu...
Source: American Journal of Hematology - May 21, 2013 Category: Hematology Authors: Ayalew Tefferi Tags: Annual Clinical Updates in Hematological Malignancies: A Continuing Medical Education Series Source Type: research

Platelets in patients with aspirin-exacerbated respiratory disease
Source: Journal of Allergy and Clinical Immunology - June 1, 2015 Category: Allergy & Immunology Tags: Continuing Medical Education examination Source Type: research

Exam 4: Regular Aspirin Use Associates With Lower Risk of Colorectal Cancers With Low Numbers of Tumor-Infiltrating Lymphocytes
Source: Gastroenterology - September 28, 2016 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research

Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis (RARS ‐T): 2017 update on diagnosis, risk‐stratification, and management
Abstract Disease OverviewRing sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. Two myeloid neoplasms defined by the presence of RS, include refractory anemia with ring sideroblasts (RARS), now classified under myelodysplastic syndromes with RS (MDS‐RS) and RARS with thrombocytosis (RARS‐T); now called myelodysplastic/myeloproliferative neoplasm with RS and thrombocytosis (MDS/MPN‐RS‐T). DiagnosisMDS‐RS is a lower risk MDS, with single or multilineage dysplasia (SLD/MLD), <5% bone marrow (BM) blasts and ≥15% BM RS (≥5% in the presence of SF3B1 mutations)....
Source: American Journal of Hematology - February 10, 2017 Category: Hematology Authors: Mrinal M. Patnaik, Ayalew Tefferi Tags: Annual Clinical Updates in Hematological Malignancies: A Continuing Medical Education Series Source Type: research

Highlights from this issue
Writing these notes for the start of the journal, I usually need to decide how focused—or wide ranging—they are going to be. By this, I mean, am I going to write about just one or two articles, or am I going to try to cover all of the journal? This month I'm particularly interested in a pair of papers about Kawasaki disease. Kawasaki disease has an illustrious history in Education and Practice, not least because a paper by Ian Maconochie from the very first issue of this journal1 is still one of our most popular downloads online. Of course, things have come a long way since 2004 in our understanding of this dis...
Source: Archives of Disease in Childhood - Education and Practice - March 14, 2013 Category: Pediatrics Authors: Wacogne, I. Tags: Immunology (including allergy), Dermatology, Medical humanities Epistle Source Type: research

Medical History, Medication Use, and Risk of Nasopharyngeal Carcinoma.
Abstract Because persistent inflammation may render the nasopharyngeal mucosa susceptible to carcinogenesis, chronic ear/nose/throat (ENT) disease and its treatment might influence the risk of nasopharyngeal carcinoma (NPC). Existing evidence is, however, inconclusive and often based on methodologically suboptimal epidemiologic studies. In a population-based case-control study in southern China, we enrolled 2532 NPC cases and 2597 controls aged 20-74 years from 2010 to 2014. Odds ratios were estimated for associations between NPC risk and history of ENT and related medications. Any history of chronic ENT disease w...
Source: Am J Epidemiol - April 26, 2018 Category: Epidemiology Authors: Xiao X, Zhang Z, Chang ET, Liu Z, Liu Q, Cai Y, Chen G, Huang QH, Xie SH, Cao SM, Shao JY, Jia WH, Zheng Y, Liao J, Chen Y, Lin L, Ernberg I, Huang G, Zeng Y, Zeng YX, Adami HO, Ye W, Guangxi Medical University Tags: Am J Epidemiol Source Type: research

Vertos Medical ’s spinal stenosis treatment wins CE mark
Vertos Medical said it has received CE mark approval for its lumbar spinal stenosis (LSS) treatment device kit. Aliso Viejo, Calif.-based Vertos said its Mild device kit enables a minimally invasive procedure to remove the cause of stenosis through a portal the size of a baby aspirin. The procedure requires no stitches, general anesthesia, implants or overnight hospital stays, the company added. Get the full story on our sister site, Medical Design & Outsourcing. The post Vertos Medical’s spinal stenosis treatment wins CE mark appeared first on MassDevice.
Source: Mass Device - February 27, 2019 Category: Medical Devices Authors: Nancy Crotti Tags: Blog Business/Financial News Featured News Well Orthopedics Surgical CE Mark Vertos Medical Source Type: news

Why Not Pot? A Review of the Brain-based Risks of Cannabis
Conclusion Evaluating the potential harms of a commonly used drug—especially a complex substance like marijuana—is a challenging but vital task. Fully informed awareness of both the potential and proven benefits and the potential and proven harms of marijuana are necessary in order to have rational discussions with patients, teens, and decision makers regarding marijuana use. Based on a review of the current literature, we suggest the mnemonic DDUMB (dependence, driving, underachievement, mental illness, and “bad to worse”) as a tool that captures several of the more well-supported, brain-based risks associated wit...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Behavioral and Cognitive Neurology Child Adol Mental Disorders Cognition Current Issue Medical Issues Neurologic Systems and Symptoms Psychiatry Psychopharmacology Review Substance Use Disorders Cannabis dependence drug-related har Source Type: research

The Safety of Continuing Low-dose Aspirin Therapy Perioperatively in the Patients had Undergone Percutaneous Nephrolithotomy: A Systematic Review and Meta-analysis
CONCLUSION: Based on our findings, transient cessation of aspirin perioperatively seems not to be necessary for patients who need PCNL complicated with the necessity of aspirin therapy. However, further well-designed prospective studies with large sample size are needed to confirm and validate our findings.PMID:35762083 | DOI:10.22037/uj.v19i.7170
Source: Urology Journal - June 28, 2022 Category: Urology & Nephrology Authors: Yang Pan Mingming Xu Jiaqi Kang Shangren Wang Xiaoqiang Liu Source Type: research